DNA Nano-Gears
Reza Mohammadzadegan and Mohammad Hossein Sheikhi

Abstract
DNA is a nanoscale material for programmable self-assembly, using the selective affinity of pairs of DNA strands to form DNA nanostructures. Self-assembly is the spontaneous self-ordering of substructures into superstructures which driven by the selective affinity of the substructures. DNA self-assembly is the most advanced and versatile system that has been experimentally demonstrated for programmable construction of patterned systems on the molecular scale. This programmability renders the scaffolding have the patterning required for fabricating complex devices made of these components. We present various strategies to assemble DNA based gears for application in nano-machines, nano-motors and nano-devices. In this paper, some fundamental parts of mechanical nano-machines with DNA blocks are designed. These kinds of nanostructures, nano-gears, are fundamental for the development of future useful molecular-level devices.